Cohen will be co-hosting with Giuliana Rancic for the show, which is scheduled to begin at 7 p.m. CDT. Rancic is an anchor on E! News and co-host of Fashion Police, and is known for her interviews on the red carpet with Hollywood's stars.
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Miss Universe is a beauty contest featuring women from across the globe. Past winners include Leila Lopes (2011) from Angola, Ximena Navarrete (2010) from Mexico and Stefania Fernandez (2009) from Venezuela.
The contestant representing the United States in 2012 is Olivia Culpo, a 20-year-old woman from Cranston, Rhode Island.
Cohen, who topped a local bestseller list after releasing his memoir, Most Talkative: Stories From the Front Lines of Pop Culture, recently returned home to St. Louis during Thanksgiving, when he dined with his family at Niche in Clayton.